Pure Red Cell Aplasia and Chromosomal Abnormality in a Patient With Lung Adenocarcinoma Receiving Immune Checkpoint Inhibitors: A Case Report

Micrographs of the bone marrow trephine biopsy. A) Normoplastic bone marrow. Erythroblasts are severely reduced, erythroblast islands are absent, and hematopoietic foci are dominated by granulocytes. B) A cluster of lymphocytes can be seen, suggesting an immunological mechanism. C) Few erythroblasts are found to be positive for glycophorin A. Most of the glycophorin A-positive cells are red blood cells.