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Research ArticleExperimental Studies
Open Access

Bio-characteristics and Efficacy Analysis of Biodegradable Poly Dioxanone Dermal Filler in a Mouse Model and Humans

SHU-YI ZHOU, SO MIN KANG, YEON JU GU, XIN RUI ZHANG, DONG KEON YON, BYUNG HO SHIN, JUNG RYUL HAM, WON KU LEE, JE GEUN JEONG, HAN JIN KWON and CHAN-YEONG HEO
In Vivo May 2023, 37 (3) 1093-1102; DOI: https://doi.org/10.21873/invivo.13184
SHU-YI ZHOU
1Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of Korea;
2Department of Plastic and Reconstructive Surgery, College of Medicine, Seoul National University, Seoul, Republic of Korea;
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SO MIN KANG
1Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of Korea;
3Korean Skin Research Center, Seongnam, Republic of Korea;
4H&BIO Corporation/R&D Center, Seongnam, Republic of Korea;
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YEON JU GU
5UltraV Co., Ltd. Research Center, Seoul, Republic of Korea;
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XIN RUI ZHANG
1Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of Korea;
2Department of Plastic and Reconstructive Surgery, College of Medicine, Seoul National University, Seoul, Republic of Korea;
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DONG KEON YON
6Center for Digital Health, Medical Science Research Institute, Kyung Hee University, Seoul, Republic of Korea
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BYUNG HO SHIN
1Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of Korea;
2Department of Plastic and Reconstructive Surgery, College of Medicine, Seoul National University, Seoul, Republic of Korea;
3Korean Skin Research Center, Seongnam, Republic of Korea;
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JUNG RYUL HAM
5UltraV Co., Ltd. Research Center, Seoul, Republic of Korea;
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WON KU LEE
5UltraV Co., Ltd. Research Center, Seoul, Republic of Korea;
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JE GEUN JEONG
5UltraV Co., Ltd. Research Center, Seoul, Republic of Korea;
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HAN JIN KWON
5UltraV Co., Ltd. Research Center, Seoul, Republic of Korea;
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CHAN-YEONG HEO
1Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of Korea;
2Department of Plastic and Reconstructive Surgery, College of Medicine, Seoul National University, Seoul, Republic of Korea;
3Korean Skin Research Center, Seongnam, Republic of Korea;
4H&BIO Corporation/R&D Center, Seongnam, Republic of Korea;
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  • For correspondence: lionheo{at}snu.ac.kr
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Article Information

vol. 37 no. 3 1093-1102
DOI 
https://doi.org/10.21873/invivo.13184
PMID 
37103107

Published By 
International Institute of Anticancer Research
Print ISSN 
0258-851X
Online ISSN 
1791-7549
History 
  • Received February 18, 2023
  • Revision received March 10, 2023
  • Accepted March 27, 2023
  • Published online April 27, 2023.

Copyright & License 
Copyright © 2023 The Author(s). Published by the International Institute of Anticancer Research. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY-NC-ND) 4.0 international license (https://creativecommons.org/licenses/by-nc-nd/4.0).

Author Information

  1. SHU-YI ZHOU1,2†,
  2. SO MIN KANG1,3,4†,
  3. YEON JU GU5†,
  4. XIN RUI ZHANG1,2,
  5. DONG KEON YON6,
  6. BYUNG HO SHIN1,2,3,
  7. JUNG RYUL HAM5,
  8. WON KU LEE5,
  9. JE GEUN JEONG5,
  10. HAN JIN KWON5 and
  11. CHAN-YEONG HEO1,2,3,4⇑
  1. 1Department of Plastic and Reconstructive Surgery, Seoul National University Bundang Hospital, Seongnam, Republic of Korea;
  2. 2Department of Plastic and Reconstructive Surgery, College of Medicine, Seoul National University, Seoul, Republic of Korea;
  3. 3Korean Skin Research Center, Seongnam, Republic of Korea;
  4. 4H&BIO Corporation/R&D Center, Seongnam, Republic of Korea;
  5. 5UltraV Co., Ltd. Research Center, Seoul, Republic of Korea;
  6. 6Center for Digital Health, Medical Science Research Institute, Kyung Hee University, Seoul, Republic of Korea
  1. Correspondence to: Chan-Yeong Heo, Department of Plastic and Reconstructive Surgery, College of Medicine, Seoul National University, 103 Daehak-ro, Jongno-gu, Seoul 03080, Republic of Korea. Tel: +82 317877222, e-mail: lionheo{at}snu.ac.kr
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Bio-characteristics and Efficacy Analysis of Biodegradable Poly Dioxanone Dermal Filler in a Mouse Model and Humans
SHU-YI ZHOU, SO MIN KANG, YEON JU GU, XIN RUI ZHANG, DONG KEON YON, BYUNG HO SHIN, JUNG RYUL HAM, WON KU LEE, JE GEUN JEONG, HAN JIN KWON, CHAN-YEONG HEO
In Vivo May 2023, 37 (3) 1093-1102; DOI: 10.21873/invivo.13184

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Bio-characteristics and Efficacy Analysis of Biodegradable Poly Dioxanone Dermal Filler in a Mouse Model and Humans
SHU-YI ZHOU, SO MIN KANG, YEON JU GU, XIN RUI ZHANG, DONG KEON YON, BYUNG HO SHIN, JUNG RYUL HAM, WON KU LEE, JE GEUN JEONG, HAN JIN KWON, CHAN-YEONG HEO
In Vivo May 2023, 37 (3) 1093-1102; DOI: 10.21873/invivo.13184
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  • Polydioxanone
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