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Research ArticleClinical Studies
Open Access

Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry

KENSUKE NISHI, SHOHEI YOSHIMOTO, SOICHIRO NISHI, TATSURO NISHI, RYUSHIRO NISHI, TOSHIYUKI TSUNODA, HIROMITSU MORITA, HIROAKI TANAKA, OSAMU HOTTA, SUSUMU YASUMASU, KENJI HIROMATSU, SENJI SHIRASAWA, TAKASHI NAKAGAWA and TAKAFUMI YAMANO
In Vivo September 2022, 36 (5) 2357-2364; DOI: https://doi.org/10.21873/invivo.12967
KENSUKE NISHI
1Section of Otolaryngology, Department of Medicine, Fukuoka Dental College, Fukuoka, Japan;
2Nishi Otolaryngology Clinic, Fukuoka, Japan;
3Department of Otolaryngology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
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  • For correspondence: knishi{at}college.fdcnet.ac.jp
SHOHEI YOSHIMOTO
4Section of Pathology, Department of Morphological Biology, Division of Biomedical Sciences, Fukuoka Dental College, Fukuoka, Japan;
5Oral Medicine Research Center, Fukuoka Dental College, Fukuoka, Japan;
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SOICHIRO NISHI
2Nishi Otolaryngology Clinic, Fukuoka, Japan;
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TATSURO NISHI
2Nishi Otolaryngology Clinic, Fukuoka, Japan;
3Department of Otolaryngology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
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RYUSHIRO NISHI
2Nishi Otolaryngology Clinic, Fukuoka, Japan;
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TOSHIYUKI TSUNODA
6Department of Cell Biology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
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HIROMITSU MORITA
7The Center for Visiting Dental Service, Fukuoka Dental College Medical and Dental General Hospital, Fukuoka, Japan;
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HIROAKI TANAKA
8Tanaka Hiroaki Clinic, Fukuoka, Japan;
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OSAMU HOTTA
9Division of Internal Medicine, Hotta Osamu Clinic (HOC), Sendai, Japan;
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SUSUMU YASUMASU
2Nishi Otolaryngology Clinic, Fukuoka, Japan;
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KENJI HIROMATSU
10Department of Microbiology and Immunology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
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SENJI SHIRASAWA
6Department of Cell Biology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
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TAKASHI NAKAGAWA
11Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
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TAKAFUMI YAMANO
1Section of Otolaryngology, Department of Medicine, Fukuoka Dental College, Fukuoka, Japan;
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Article Information

vol. 36 no. 5 2357-2364
DOI 
https://doi.org/10.21873/invivo.12967
PMID 
36099101

Published By 
International Institute of Anticancer Research
Print ISSN 
0258-851X
Online ISSN 
1791-7549
History 
  • Received June 24, 2022
  • Revision received July 18, 2022
  • Accepted July 20, 2022
  • Published online September 7, 2022.

Copyright & License 
Copyright © 2022 The Author(s). Published by the International Institute of Anticancer Research. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY-NC-ND) 4.0 international license (https://creativecommons.org/licenses/by-nc-nd/4.0).

Author Information

  1. KENSUKE NISHI1,2,3⇑,
  2. SHOHEI YOSHIMOTO4,5,
  3. SOICHIRO NISHI2,
  4. TATSURO NISHI2,3,
  5. RYUSHIRO NISHI2,
  6. TOSHIYUKI TSUNODA6,
  7. HIROMITSU MORITA7,
  8. HIROAKI TANAKA8,
  9. OSAMU HOTTA9,
  10. SUSUMU YASUMASU2,
  11. KENJI HIROMATSU10,
  12. SENJI SHIRASAWA6,
  13. TAKASHI NAKAGAWA11 and
  14. TAKAFUMI YAMANO1
  1. 1Section of Otolaryngology, Department of Medicine, Fukuoka Dental College, Fukuoka, Japan;
  2. 2Nishi Otolaryngology Clinic, Fukuoka, Japan;
  3. 3Department of Otolaryngology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
  4. 4Section of Pathology, Department of Morphological Biology, Division of Biomedical Sciences, Fukuoka Dental College, Fukuoka, Japan;
  5. 5Oral Medicine Research Center, Fukuoka Dental College, Fukuoka, Japan;
  6. 6Department of Cell Biology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
  7. 7The Center for Visiting Dental Service, Fukuoka Dental College Medical and Dental General Hospital, Fukuoka, Japan;
  8. 8Tanaka Hiroaki Clinic, Fukuoka, Japan;
  9. 9Division of Internal Medicine, Hotta Osamu Clinic (HOC), Sendai, Japan;
  10. 10Department of Microbiology and Immunology, Faculty of Medicine, Fukuoka University, Fukuoka, Japan;
  11. 11Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
  1. Correspondence to: Kensuke Nishi, MD, Ph.D., Section of Otolaryngology, Department of Medicine, Fukuoka Dental College, Fukuoka, Japan, 2-15-1 Tamura, Sawara-ku, Fukuoka, 814-0193, Japan. Tel: +81 928010411, Fax: +81 928013678, e-mail: knishi{at}college.fdcnet.ac.jp
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Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry
KENSUKE NISHI, SHOHEI YOSHIMOTO, SOICHIRO NISHI, TATSURO NISHI, RYUSHIRO NISHI, TOSHIYUKI TSUNODA, HIROMITSU MORITA, HIROAKI TANAKA, OSAMU HOTTA, SUSUMU YASUMASU, KENJI HIROMATSU, SENJI SHIRASAWA, TAKASHI NAKAGAWA, TAKAFUMI YAMANO
In Vivo Sep 2022, 36 (5) 2357-2364; DOI: 10.21873/invivo.12967

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Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry
KENSUKE NISHI, SHOHEI YOSHIMOTO, SOICHIRO NISHI, TATSURO NISHI, RYUSHIRO NISHI, TOSHIYUKI TSUNODA, HIROMITSU MORITA, HIROAKI TANAKA, OSAMU HOTTA, SUSUMU YASUMASU, KENJI HIROMATSU, SENJI SHIRASAWA, TAKASHI NAKAGAWA, TAKAFUMI YAMANO
In Vivo Sep 2022, 36 (5) 2357-2364; DOI: 10.21873/invivo.12967
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Keywords

  • Epipharyngeal abrasive therapy (EAT)
  • influenza
  • influenza A virus (IAV)
  • voltage-dependent Ca2+ channel (Cav1.2)
  • chronic epipharyngitis
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