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Review ArticleReview

The Impact of ACE and ACE2 Gene Polymorphisms in Pulmonary Diseases Including COVID-19

IPHIGENIA GINTONI, MARIA ADAMOPOULOU and CHRISTOS YAPIJAKIS
In Vivo January 2022, 36 (1) 13-29; DOI: https://doi.org/10.21873/invivo.12672
IPHIGENIA GINTONI
1Unit of Orofacial Genetics, 1st Department of Pediatrics, National Kapodistrian University of Athens, “Hagia Sophia” Children’s Hospital, Athens, Greece;
2Department of Molecular Genetics, Cephalogenetics Center, Athens, Greece;
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MARIA ADAMOPOULOU
2Department of Molecular Genetics, Cephalogenetics Center, Athens, Greece;
3Department of Biomedical Sciences, University of West Attica, Athens, Greece;
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CHRISTOS YAPIJAKIS
1Unit of Orofacial Genetics, 1st Department of Pediatrics, National Kapodistrian University of Athens, “Hagia Sophia” Children’s Hospital, Athens, Greece;
2Department of Molecular Genetics, Cephalogenetics Center, Athens, Greece;
4University Research Institute of Maternal and Child Health and Precision Medicine, National and Kapodistrian University of Athens, Athens, Greece
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  • For correspondence: cyapi{at}med.uoa.gr
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Article Information

vol. 36 no. 1 13-29
DOI 
https://doi.org/10.21873/invivo.12672
PMID 
34972696

Published By 
International Institute of Anticancer Research
Print ISSN 
0258-851X
Online ISSN 
1791-7549
History 
  • Received July 29, 2021
  • Revision received October 8, 2021
  • Accepted October 12, 2021
  • Published online December 30, 2021.

Copyright & License 
Copyright © 2022 The Author(s). Published by the International Institute of Anticancer Research.

Author Information

  1. IPHIGENIA GINTONI1,2,
  2. MARIA ADAMOPOULOU2,3 and
  3. CHRISTOS YAPIJAKIS1,2,4⇑
  1. 1Unit of Orofacial Genetics, 1st Department of Pediatrics, National Kapodistrian University of Athens, “Hagia Sophia” Children’s Hospital, Athens, Greece;
  2. 2Department of Molecular Genetics, Cephalogenetics Center, Athens, Greece;
  3. 3Department of Biomedical Sciences, University of West Attica, Athens, Greece;
  4. 4University Research Institute of Maternal and Child Health and Precision Medicine, National and Kapodistrian University of Athens, Athens, Greece
  1. Correspondence to: Associate Professor Christos Yapijakis, DMD, MS, Ph.D., “Cephalogenetics” Center, Philaretou 88, Kallithea 17675, Athens, Greece. Tel: +30 2109595772, e-mail: cyapi{at}med.uoa.gr
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January-February 2022
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The Impact of ACE and ACE2 Gene Polymorphisms in Pulmonary Diseases Including COVID-19
IPHIGENIA GINTONI, MARIA ADAMOPOULOU, CHRISTOS YAPIJAKIS
In Vivo Jan 2022, 36 (1) 13-29; DOI: 10.21873/invivo.12672

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The Impact of ACE and ACE2 Gene Polymorphisms in Pulmonary Diseases Including COVID-19
IPHIGENIA GINTONI, MARIA ADAMOPOULOU, CHRISTOS YAPIJAKIS
In Vivo Jan 2022, 36 (1) 13-29; DOI: 10.21873/invivo.12672
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  • Article
    • Abstract
    • The Renin-angiotensin System (RAS)
    • RAS in Lung Disease: The Involvement of ACE and ACE2
    • Chronic Obstructive Pulmonary Disease and ACE I/D Polymorphism
    • Pulmonary Hypertension and ACE I/D Polymorphism
    • Asthma and ACE I/D Polymorphism
    • Acute Lung Injury, Acute Respiratory Distress Syndrome and ACE I/D Polymorphism
    • Lung Cancer and ACE I/D Polymorphism
    • SARS-CoV-2 Infection and COVID-19
    • ACE I/D Polymorphism in SARS-CoV-2 Infection and COVID-19
    • ACE2 Gene Polymorphisms in SARS-CoV-2 Infection and COVID-19
    • Pulmonary Sarcoidosis and ACE I/D Polymorphism
    • Discussion
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
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Keywords

  • Lung
  • respiratory system
  • pulmonary disease
  • renin-angiotensin system
  • ACE
  • ACE2
  • polymorphism
  • Asthma
  • lung cancer
  • pulmonary sarcoidosis
  • SARS-CoV-2
  • COVID-19
  • coronavirus
  • review
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