Table of Contents

Clinical Studies

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  Repeated 5-aminolevulinic Acid Instillations During Follow-up in Non-muscle-invasive Bladder Cancer: A Randomized Study

  EIJA KELLONIEMI, RIIKKA JÄRVINEN, PEKKA HELLSTRÖM, ERKKI RINTALA, SIRPA AALTOMAA, TAINA ISOTALO, KALMER INNOS and EERO KAASINEN

  In Vivo May 2021, 35 (3) 1561-1568; DOI: https://doi.org/10.21873/invivo.12411
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  Validation of a Graded Prognostic Model in Patients With Brain Metastases Treated With Whole-brain Radiotherapy Instead of Radiosurgery

  CARSTEN NIEDER, BÅRD MANNSÅKER and ROSALBA YOBUTA

  In Vivo May 2021, 35 (3) 1569-1572; DOI: https://doi.org/10.21873/invivo.12412
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  Therapeutic and Clinical Outcomes of Robot-assisted Partial Nephrectomy Versus Cryoablation for T1 Renal Cell Carcinoma

  TOSHIHIRO UEMURA, TAIGO KATO, AKIRA NAGAHARA, ATSUNARI KAWASHIMA, KOJI HATANO, TAKESHI UJIKE, YUSUKE ONO, HIROKI HIGASHIHARA, KAZUTOSHI FUJITA, SHINICHIRO FUKUHARA, HIROSHI KIUCHI, RYOICHI IMAMURA, NORIYUKI TOMIYAMA, NORIO NONOMURA and MOTOHIDE UEMURA

  In Vivo May 2021, 35 (3) 1573-1579; DOI: https://doi.org/10.21873/invivo.12413
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  Eyeglasses Reduce Risk of COVID-19 Infection

  STEVEN LEHRER and PETER RHEINSTEIN

  In Vivo May 2021, 35 (3) 1581-1582; DOI: https://doi.org/10.21873/invivo.12414
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  Phenotype and Surgical Treatment in a Case of Proteus Syndrome With Craniofacial and Oral Findings

  REINHARD E. FRIEDRICH

  In Vivo May 2021, 35 (3) 1583-1594; DOI: https://doi.org/10.21873/invivo.12415
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  Associations Between Time to Treatment Start and Survival in Patients With Lung Cancer

  TRINE STOKSTAD, SVEINUNG SØRHAUG, TORE AMUNDSEN and BJØRN H. GRØNBERG

  In Vivo May 2021, 35 (3) 1595-1603; DOI: https://doi.org/10.21873/invivo.12416
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  Investigation of Circulating miRNA-133, miRNA-26, and miRNA-378 as Candidate Biomarkers for Left Ventricular Hypertrophy

  ZERRIN BARUT, AYCA TURER CABBAR, SEDA GULEC YILMAZ, FATMA TUBA AKDENIZ, MUSTAFA AYTEK SIMSEK, BETUL CAPAR, MUZAFFER DEGERTEKIN, ALTAY BURAK DALAN, HALIT YEREBAKAN and TURGAY ISBIR

  In Vivo May 2021, 35 (3) 1605-1610; DOI: https://doi.org/10.21873/invivo.12417
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  Impact of K-Ras Over-expression in Laryngeal Squamous Cell Carcinoma

  VASILEIOS PAPANIKOLAOU, ARISTEIDIS CHRYSOVERGIS, STYLIANOS MASTRONIKOLIS, EVANGELOS TSIAMBAS, VASILEIOS RAGOS, DIMITRIOS PESCHOS, DESPOINA SPYROPOULOU, PAVLOS PANTOS, ATHANASIOS NIOTIS, NICHOLAS MASTRONIKOLIS and EFTHYMIOS KYRODIMOS

  In Vivo May 2021, 35 (3) 1611-1615; DOI: https://doi.org/10.21873/invivo.12418
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  Intravenous Iron Replacement Therapy Improves Cardiovascular Outcomes in Hemodialysis Patients

  MATTEO RIGHINI, VITTORIO DALMASTRI, IRENE CAPELLI, CLAUDIO ORSI, GABRIELE DONATI, MARIA GIOVANNA PALLOTTI, CHIARA PEDONE, GIANNI CASELLA, PASQUALE CHIECO and GAETANO LA MANNA

  In Vivo May 2021, 35 (3) 1617-1624; DOI: https://doi.org/10.21873/invivo.12419
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  Leukocyte Esterase and Glucose Reagent Test Can Rule in and Rule out Septic Arthritis

  LOUISA KOLBECK, MARCO HAERTLÉ, TILMAN GRAULICH, MAX ETTINGER, EDUARDO M. SUERO, CHRISTIAN KRETTEK and MOHAMED OMAR

  In Vivo May 2021, 35 (3) 1625-1632; DOI: https://doi.org/10.21873/invivo.12420
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  Ultrasound Echogenicity of Papillary Thyroid Cancer Is Affected by Tumor Growth Patterns and Tumor Fibrosis

  YUN-SUNG LIM, YOON SE LEE, JIN-CHOON LEE, SEOK-MAN SON, DONG-HOON SHIN, SANG SOO KIM, IN-JU KIM and BYUNG-JOO LEE

  In Vivo May 2021, 35 (3) 1633-1640; DOI: https://doi.org/10.21873/invivo.12421
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  Validation of the Effectiveness of Neutrophil-to-lymphocyte Ratio (NLR) as a Predictive Factor in Patients Undergoing Prostate Biopsy With Prostate Specific Antigen (PSA) Between 4.0 and 10.0 ng/ml

  HIROSHI MASUDA, KOSUKE MIKAMI, KOTARO OTSUKA, KYOKUSIN HOU, TAKAHITO SUYAMA, KAZUHIRO ARAKI, SATOKO KOJIMA and YUKIO NAYA

  In Vivo May 2021, 35 (3) 1641-1646; DOI: https://doi.org/10.21873/invivo.12422
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  Association Between Renal Adverse Effects and Mortality in Patients With Hepatocellular Carcinoma Treated With Lenvatinib

  YOSHINOSUKE SHIMAMURA, KOKI ABE, TAKUTO MAEDA, TAKESHI MATSUI, ATSUSHI ISHIGURO and HIDEKI TAKIZAWA

  In Vivo May 2021, 35 (3) 1647-1653; DOI: https://doi.org/10.21873/invivo.12423
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  Pocket Creation and Ring-thread Traction Facilitates Colorectal Endoscopic Submucosal Dissection for Non-experts

  AYAKO FUJIMORI, NORIKO NISHIYAMA, HIDEKI KOBARA, KAZUHIRO KODUKA, NAOYA TADA, TAKANORI MATSUI, TAIGA CHIYO, NOBUYA KOBAYASHI, SHINTARO FUJIHARA, TATSUO YACHIDA, KEIICHI OKANO, YASUYUKI SUZUKI, DAISUKE NAKANO, AKIRA NISHIYAMA and TSUTOMU MASAKI

  In Vivo May 2021, 35 (3) 1655-1660; DOI: https://doi.org/10.21873/invivo.12424
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  Clinical Effect of End-range Maitland Mobilization in the Management of Knee Osteoarthritis – A Pilot Study

  MIKLÓS POZSGAI, ERZSÉBET KÖVESDI, BALÁZS NÉMETH, ISTVÁN KISS, NELLI FARKAS, TAMÁS ATLASZ, MÁRK VÁCZI and NÓRA NUSSER

  In Vivo May 2021, 35 (3) 1661-1668; DOI: https://doi.org/10.21873/invivo.12425
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  Combined LOCalizer™ and Intraoperative Ultrasound Localization: First Experience in Localization of Non-palpable Breast Cancer

  SIMONA PARISI, ROBERTO RUGGIERO, GIORGIA GUALTIERI, MARIACHIARA LANZA VOLPE, SERENA RINALDI, GIUSIANA NESTA, LIDIJA BOGDANOVICH, FRANCESCO SAVERIO LUCIDO, SALVATORE TOLONE, DOMENICO PARMEGGIANI, CLAUDIO GAMBARDELLA and LUDOVICO DOCIMO

  In Vivo May 2021, 35 (3) 1669-1676; DOI: https://doi.org/10.21873/invivo.12426
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  Myocardial Fibrosis as a Predictor of Ventricular Arrhythmias in Patients With Non-ischemic Cardiomyopathy

  CĂLIN SCHIAU, DANIEL-CORNELIU LEUCUȚA, SORIN MARIAN DUDEA and SIMONA MANOLE

  In Vivo May 2021, 35 (3) 1677-1685; DOI: https://doi.org/10.21873/invivo.12427
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  Case Series of Pleomorphic Carcinoma of the Lung Treated With Immune Checkpoint Inhibitors

  KANA HAYASHI, KOTARO TOKUI, MINEHIKO INOMATA, KENJI AZECHI, ISAMI MIZUSHIMA, NAOKI TAKATA, CHIHIRO TAKA, SEISUKE OKAZAWA, KENTA KAMBARA, SHINGO IMANISHI, TOSHIRO MIWA, RYUJI HAYASHI, SHOKO MATSUI, SATOSHI NOMURA and KAZUYUKI TOBE

  In Vivo May 2021, 35 (3) 1687-1692; DOI: https://doi.org/10.21873/invivo.12428
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  Pathological Significance and Prognostic Roles of Thrombospondin-3, 4 and 5 in Bladder Cancer

  JUNKI HARADA, YASUYOSHI MIYATA, KYOHEI ARAKI, TSUYOSHI MATSUDA, YOSHIAKI NAGASHIMA, YUTA MUKAE, KENSUKE MISTUNARI, TOMOHIRO MATSUO, KOJIRO OHBA, YASUSHI MOCHIZUKI and HIDEKI SAKAI

  In Vivo May 2021, 35 (3) 1693-1701; DOI: https://doi.org/10.21873/invivo.12429
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  Sarcopenia and Visceral Metastasis at Cabazitaxel Initiation Predict Prognosis in Patients With Castration-resistant Prostate Cancer Receiving Cabazitaxel Chemotherapy

  HIROAKI IWAMOTO, HIROSHI KANO, TAKAFUMI SHIMADA, RENATO NAITO, TOMOYUKI MAKINO, SUGURU KADOMOTO, HIROSHI YAEGASHI, KAZUYOSHI SHIGEHARA, KOUJI IZUMI, YOSHIFUMI KADONO and ATSUSHI MIZOKAMI

  In Vivo May 2021, 35 (3) 1703-1709; DOI: https://doi.org/10.21873/invivo.12430
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  Neurofibromatosis Type 1 With Cherubism-like Phenotype, Multiple Osteolytic Bone Lesions of Lower Extremities, and Alagille-syndrome: Case Report With Literature Survey

  REINHARD E. FRIEDRICH, JOZEF ZUSTIN, ANDREAS M. LUEBKE, THORSTEN ROSENBAUM, MARTIN GOSAU, CHRISTIAN HAGEL, FELIX K. KOHLRUSCH, ILSE WIELAND and MARTIN ZENKER

  In Vivo May 2021, 35 (3) 1711-1736; DOI: https://doi.org/10.21873/invivo.12431
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  Effect of Prophylactic Anti-emetics on Opioid-induced Nausea and Vomiting: A Retrospective Observational Cohort Study

  TOMOKI TAMURA, KEITA KAWAKADO, GO MAKIMOTO, MASAMOTO NAKANISHI and SHOICHI KUYAMA

  In Vivo May 2021, 35 (3) 1737-1742; DOI: https://doi.org/10.21873/invivo.12432
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  Efficacy of Cabozantinib in Metastatic Papillary Renal Cell Carcinoma Following Ineffective Treatment With Initial Therapy of Nivolumab and Ipilimumab

  HIDEKAZU TACHIBANA, YUDAI ISHIYAMA, MAKI YOSHINO, KAORI YAMASHITA, DAISUKE TOKI and TSUNENORI KONDO

  In Vivo May 2021, 35 (3) 1743-1747; DOI: https://doi.org/10.21873/invivo.12433
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  Different Characteristics of Serum Alfa Fetoprotein and Serum Des-gamma-carboxy Prothrombin in Resected Hepatocellular Carcinoma

  MASAMICHI HAYASHI, SUGURU YAMADA, NAO TAKANO, YUKIYASU OKAMURA, HIDEKI TAKAMI, YOSHIKUNI INOKAWA, FUMINORI SONOHARA, NOBUTAKE TANAKA, DAI SHIMIZU, NORIFUMI HATTORI, MITSURO KANDA, CHIE TANAKA, GORO NAKAYAMA, MASAHIKO KOIKE and YASUHIRO KODERA

  In Vivo May 2021, 35 (3) 1749-1760; DOI: https://doi.org/10.21873/invivo.12434
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  Association Between Serum Alarmin Levels and Disease-specific Indices in Patients With Anti-neutrophil Cytoplasmic Antibody-associated Vasculitis

  SUNG SOO AHN, TAEJUN YOON, JASON JUNGSIK SONG, YONG-BEOM PARK and SANG-WON LEE

  In Vivo May 2021, 35 (3) 1761-1768; DOI: https://doi.org/10.21873/invivo.12435
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  Diagnostic Utility of p62 Expression in Intranuclear Inclusions in Thyroid Core Needle Biopsy Specimens

  HYO JUNG AN, MIN HYE KIM, JI MIN NA, JUNG WOOK YANG, HYE JIN BAEK, KYEONG HWA RYU and DAE HYUN SONG

  In Vivo May 2021, 35 (3) 1769-1775; DOI: https://doi.org/10.21873/invivo.12436
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  Undervaluation of Radiotherapy for Gross Desmoid Tumors: The Need for Absolute Volume Assessment

  YEON JOO KIM, SI YEOL SONG, WANLIM KIM, JONGSEOK LEE, JIN-HEE AHN, JEONG EUN KIM, HYE WON CHUNG, SEONG-YUN JEONG and EUN KYUNG CHOI

  In Vivo May 2021, 35 (3) 1777-1784; DOI: https://doi.org/10.21873/invivo.12437
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  Granulocyte Colony-stimulating Factor Producing Oropharyngeal Squamous Cell Carcinoma

  GREGORY SCHURMANN, MARTIN ZWEIFEL, ROLAND GIGER, TILMAN T. RAU, SARAH VINZENS, MATTHIAS S. DETTMER and YOJENA KURIAN

  In Vivo May 2021, 35 (3) 1785-1790; DOI: https://doi.org/10.21873/invivo.12438
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  Association of Psychometric Indices and Normal Electrodiagnostic Studies in Referral for Suspected Carpal Tunnel Syndrome

  MARIANNA PAPADOPOULOU, GEORGIOS TSIVGOULIS, IOANNA CHATZI, LINA PALAIODIMOU, MARIANNA BREGIANNI, KONSTANTINOS VOUMVOURAKIS and IOANNIS MICHOPOULOS

  In Vivo May 2021, 35 (3) 1791-1797; DOI: https://doi.org/10.21873/invivo.12439
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  Retrospective Study of the Effects of Post-nasal Drip Symptoms on Cough Duration

  TAKEO NAKAJIMA, TATSUYA NAGANO and YOSHIHIRO NISHIMURA

  In Vivo May 2021, 35 (3) 1799-1803; DOI: https://doi.org/10.21873/invivo.12440
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  Long-term Response After Stopping Immunotherapy in a Patient With Metastatic Renal Cancer

  BOGDAN HAINEALA, ANCA ZGURA, CAMELIA DIACONU, CLAUDIA MEHEDINTU, XENIA BACINSCHI and RODICA MARICELA ANGHEL

  In Vivo May 2021, 35 (3) 1805-1810; DOI: https://doi.org/10.21873/invivo.12441
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  Increased Incidence of Stress-related Tic Habit Cough in Children During the Recent Greek Financial Crisis

  ATHINA PAPADOPOULOU, DESPOINA-ZOE T. MERMIRI, GEORGIOS GRITZELAS, OURANIA TSOURIDI, ELENI DIMARA, CHRISTOS YAPIJAKIS and GEORGE P. CHROUSOS

  In Vivo May 2021, 35 (3) 1811-1820; DOI: https://doi.org/10.21873/invivo.12442
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  Quality of Life in Early Breast Cancer Patients: A Prospective Observational Study Using the FACT-B Questionnaire

  LUCIA ANNA URSINI, MARIANNA NUZZO, CONSUELO ROSA, FIORELLA CRISTINA DI GUGLIELMO, MONICA DI TOMMASO, MARIANNA TRIGNANI, MARZIA BORGIA, ALBINA ALLAJBEJ, FABIOLA PATANI, CLELIA DI CARLO, ANNAMARIA PORRECA, MARTA DI NICOLA, DOMENICO GENOVESI and LUCIANA CARAVATTA

  In Vivo May 2021, 35 (3) 1821-1828; DOI: https://doi.org/10.21873/invivo.12443
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  Clinical Characteristics and Outcome of Pathologic N0 Non-small Cell Lung Cancer Patients With False Positive Mediastinal Lymph Node Metastasis on FDG PET-CT

  KYU YEAN KIM, HYE LIM PARK, HYE SEON KANG, HWA YOUNG LEE, IE RYUNG YOO, SANG HAAK LEE and CHANG DONG YEO

  In Vivo May 2021, 35 (3) 1829-1836; DOI: https://doi.org/10.21873/invivo.12444
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  Periprosthetic Fracture Resembling Atypical Femoral Fracture After Fixation With Retrograde Intramedullary Nail in Elderly Women: A Report of Two Cases

  YOJIRO TAKAHASHI, SATOSHI HATASHITA, YUMETAKA SHINDEN, MASAYUKI ITO, YOICHI KANEUCHI, MICHIYUKI HAKOZAKI and SHINICHI KONNO

  In Vivo May 2021, 35 (3) 1837-1842; DOI: https://doi.org/10.21873/invivo.12445
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  Assessment of Blood Plasma Free-amino Acid Levels in Infertile Men

  TAKAYUKI SUGIYAMA, HIROSHI TERADA and HIDEAKI MIYAKE

  In Vivo May 2021, 35 (3) 1843-1847; DOI: https://doi.org/10.21873/invivo.12446
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  Acute Toxicity in Hypofractionated/Stereotactic Prostate Radiotherapy of Elderly Patients: Use of the Image-guided Radio Therapy (IGRT) Clarity System

  ROSSELLA DI FRANCO, VALENTINA BORZILLO, DOMINGO ALBERTI, GIANLUCA AMETRANO, ANGELA PETITO, ANDREA COPPOLARO, ILARIA TARANTINO, SABRINA ROSSETTI, SANDRO PIGNATA, GELSOMINA IOVANE, SISTO PERDONÀ, GIUSEPPE QUARTO, GIOVANNI GRIMALDI, ALESSANDRO IZZO, LUIGI CASTALDO, RAFFAELE MUSCARIELLO, MARCELLO SERRA, GAETANO FACCHINI and PAOLO MUTO

  In Vivo May 2021, 35 (3) 1849-1856; DOI: https://doi.org/10.21873/invivo.12447
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  A Meta-Analysis for Using Radiomics to Predict Complete Pathological Response in Esophageal Cancer Patients Receiving Neoadjuvant Chemoradiation

  YUNG-SHUO KAO and YEN HSU

  In Vivo May 2021, 35 (3) 1857-1863; DOI: https://doi.org/10.21873/invivo.12448
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  Rare Nivolumab-associated Super Hyper Progressive Disease in Patients With Advanced Gastric Cancer

  YUTARO KUBOTA, KIYOSHI YOSHIMURA, KAZUYUKI HAMADA, YUYA HIRASAWA, MIDORI SHIDA, MAKOTO TANIGUCHI, HIROTO MATSUI, HIROTSUGU ARIIZUMI, TOMOYUKI ISHIGURO, NORIHIRO SUZUKI, RYOTARO OHKUMA, TAKEHIKO SAMBE, HIROO ISHIDA, ATSUSHI HORIIKE, SATOSHI WADA, JUNJI TSURUTANI, SANJU IWAMOTO, NAOKI UCHIDA, YUJI KIUCHI, SHINICHI KOBAYASHI and TAKUYA TSUNODA

  In Vivo May 2021, 35 (3) 1865-1875; DOI: https://doi.org/10.21873/invivo.12449
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  Lung Cancer, Covid-19 Infections and Chemotherapy

  BOGDAN HAINEALA, ANCA ZGURA, DUMITRU CRISTINEL BADIU, LAURA ILIESCU, RODICA MARICELA ANGHEL and XENIA ELENA BACINSCHI

  In Vivo May 2021, 35 (3) 1877-1880; DOI: https://doi.org/10.21873/invivo.12450
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  Treatment of Capecitabine Corneal Side Effects With Autologous Blood-derived Serum Eye Drops

  FEDERICO DI STASO, IRENE GATTAZZO, BEATRICE TAURELLI SALIMBENI, ALESSANDRO LAMBIASE, GIANLUCA SCUDERI, SILVIO DI STASO and MARCO CIANCAGLINI

  In Vivo May 2021, 35 (3) 1881-1884; DOI: https://doi.org/10.21873/invivo.12451
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  Thrombotic Microangiopathy: A Rare Breast Cancer-associated Complication Treated Successfully With Doxorubicin and Cyclophosphamide

  SAMUEL JALALI, DAKOTA JENNEMAN, ANKITA TANDON and HUNG KHONG

  In Vivo May 2021, 35 (3) 1885-1888; DOI: https://doi.org/10.21873/invivo.12452
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  Pembrolizumab Versus Combined Chemotherapy With Gemcitabine and Paclitaxel: A Comparative Assessment of Clinical Outcomes in Patients With Platinum-refractory Advanced Urothelial Cancer

  AYANA TAKEMURA, YUTO MATSUSHITA, KEITA TAMURA, TAKAYUKI SUGIYAMA, MASAO NAGATA, ATSUSHI OTSUKA and HIDEAKI MIYAKE

  In Vivo May 2021, 35 (3) 1889-1894; DOI: https://doi.org/10.21873/invivo.12453
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  Immune-modulating Effect of Korean Red Ginseng by Balancing the Ratio of Peripheral T Lymphocytes in Bile Duct or Pancreatic Cancer Patients With Adjuvant Chemotherapy

  IM-KYUNG KIM, KANG YOUNG LEE, JEONGHYUN KANG, JOON SEONG PARK and JOON JEONG

  In Vivo May 2021, 35 (3) 1895-1900; DOI: https://doi.org/10.21873/invivo.12454
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  Endoventricular Pericardial Patch Repair of a Giant Left Posterior Ventricular Aneurysm

  OVIDIU STIRU, ROXANA CARMEN GEANA, REZA NAYYERANI, ANDREEA SIMINA CHIBULCUTEAN, ADRIAN TULIN, LAURA RADUCU, NICOLAE BACALBASA, IRINA BALESCU, CAMELIA DIACONU, FLORENTINA FURTUNESCU, DANIEL RADAVOI and VLAD ANTON ILIESCU

  In Vivo May 2021, 35 (3) 1901-1905; DOI: https://doi.org/10.21873/invivo.12455