Weak-evidence Fusion Candidates Detected by a FusionPlex Assay Using the Ion Torrent System

SHIRO FUJITA; KATSUHIRO MASAGO; EIICHI SASAKI; SATOSHI TSUKUSHI; YOSHITSUGU HORIO; HIROAKI KURODA; TOYOAKI HIDA

doi:10.21873/invivo.12342

Research ArticleClinical Studies

Weak-evidence Fusion Candidates Detected by a FusionPlex Assay Using the Ion Torrent System

SHIRO FUJITA, KATSUHIRO MASAGO, EIICHI SASAKI, SATOSHI TSUKUSHI, YOSHITSUGU HORIO, HIROAKI KURODA and TOYOAKI HIDA

In Vivo March 2021, 35 (2) 993-998; DOI: https://doi.org/10.21873/invivo.12342

SHIRO FUJITA

1Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan;

2Department of Respiratory Medicine, Kobe Central Hospital, Kobe, Japan;

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For correspondence: jp.shirofujita{at}gmail.com

KATSUHIRO MASAGO

1Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan;

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EIICHI SASAKI

1Department of Pathology and Molecular Diagnostics, Aichi Cancer Center, Nagoya, Japan;

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SATOSHI TSUKUSHI

3Department of Orthopaedic Surgery, Aichi Cancer Center, Nagoya, Japan;

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YOSHITSUGU HORIO

4Department of Thoracic Oncology, Aichi Cancer Center, Nagoya, Japan;

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HIROAKI KURODA

5Department of Thoracic Surgery, Aichi Cancer Center, Nagoya, Japan

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TOYOAKI HIDA

4Department of Thoracic Oncology, Aichi Cancer Center, Nagoya, Japan;

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Figure 1.
Workflow for gene fusion analysis of clinical samples using the FusionPlex platform.
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Figure 2.
A flow chart showing the processing performed by the Archer Analysis software. Details of positive evidence criteria and negative evidence criteria are described in Table I and Table II, respectively.

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Weak-evidence Fusion Candidates Detected by a FusionPlex Assay Using the Ion Torrent System

SHIRO FUJITA, KATSUHIRO MASAGO, EIICHI SASAKI, SATOSHI TSUKUSHI, YOSHITSUGU HORIO, HIROAKI KURODA, TOYOAKI HIDA

In Vivo Mar 2021, 35 (2) 993-998; DOI: 10.21873/invivo.12342

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Weak-evidence Fusion Candidates Detected by a FusionPlex Assay Using the Ion Torrent System

SHIRO FUJITA, KATSUHIRO MASAGO, EIICHI SASAKI, SATOSHI TSUKUSHI, YOSHITSUGU HORIO, HIROAKI KURODA, TOYOAKI HIDA

In Vivo Mar 2021, 35 (2) 993-998; DOI: 10.21873/invivo.12342

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Keywords

Next-generation sequencing
Non-small cell lung cancer
Sarcoma
fusion gene
Ion Torrent
FusionPlex

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