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Research ArticleClinical Studies

Efficacy of Axitinib After Nivolumab Failure in Metastatic Renal Cell Carcinoma

HIROKI ISHIHARA, TOSHIO TAKAGI, TSUNENORI KONDO, HIRONORI FUKUDA, HIDEKAZU TACHIBANA, KAZUHIKO YOSHIDA, JUNPEI IIZUKA, MASAYOSHI OKUMI, HIDEKI ISHIDA and KAZUNARI TANABE
In Vivo May 2020, 34 (3) 1541-1546; DOI: https://doi.org/10.21873/invivo.11943
HIROKI ISHIHARA
1Department of Urology, Tokyo Women's Medical University, Tokyo, Japan
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TOSHIO TAKAGI
1Department of Urology, Tokyo Women's Medical University, Tokyo, Japan
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TSUNENORI KONDO
2Department of Urology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan
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  • For correspondence: kondo.tsunenori{at}twmu.ac.jp
HIRONORI FUKUDA
1Department of Urology, Tokyo Women's Medical University, Tokyo, Japan
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HIDEKAZU TACHIBANA
2Department of Urology, Tokyo Women's Medical University Medical Center East, Tokyo, Japan
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KAZUHIKO YOSHIDA
1Department of Urology, Tokyo Women's Medical University, Tokyo, Japan
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JUNPEI IIZUKA
1Department of Urology, Tokyo Women's Medical University, Tokyo, Japan
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MASAYOSHI OKUMI
1Department of Urology, Tokyo Women's Medical University, Tokyo, Japan
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HIDEKI ISHIDA
1Department of Urology, Tokyo Women's Medical University, Tokyo, Japan
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KAZUNARI TANABE
1Department of Urology, Tokyo Women's Medical University, Tokyo, Japan
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    Figure 1.

    Waterfall plot for maximum changes of targeted lesions from baseline. *Patient whose best tumor response was diagnosed as progressive disease based on the RECIST v.1.1. because of the appearance of new lesions. PD: Progressive disease; SD: stable disease; PR: partial response.

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    Figure 2.

    Progression-free and overall survival after the initiation of axitinib. CI: Confidence interval; N.R.: not reached; PFS: progression-free survival; OS: overall survival.

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    Figure 3.

    Timing and duration of distinct systemic therapies in first-line tyrosine kinase inhibitors, second-line nivolumab, and third-line axitinib.

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Vol. 34, Issue 3
May-June 2020
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Efficacy of Axitinib After Nivolumab Failure in Metastatic Renal Cell Carcinoma
HIROKI ISHIHARA, TOSHIO TAKAGI, TSUNENORI KONDO, HIRONORI FUKUDA, HIDEKAZU TACHIBANA, KAZUHIKO YOSHIDA, JUNPEI IIZUKA, MASAYOSHI OKUMI, HIDEKI ISHIDA, KAZUNARI TANABE
In Vivo May 2020, 34 (3) 1541-1546; DOI: 10.21873/invivo.11943

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Efficacy of Axitinib After Nivolumab Failure in Metastatic Renal Cell Carcinoma
HIROKI ISHIHARA, TOSHIO TAKAGI, TSUNENORI KONDO, HIRONORI FUKUDA, HIDEKAZU TACHIBANA, KAZUHIKO YOSHIDA, JUNPEI IIZUKA, MASAYOSHI OKUMI, HIDEKI ISHIDA, KAZUNARI TANABE
In Vivo May 2020, 34 (3) 1541-1546; DOI: 10.21873/invivo.11943
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Keywords

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