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Investigating the Optimal Time for Intrauterine Human Chorionic Gonadotropin Infusion in Order to Improve IVF Outcome: A Systematic Review and Meta-Analysis

MARA SIMOPOULOU, KONSTANTINOS SFAKIANOUDIS, EVANGELOS MAZIOTIS, PETROULA TSIOULOU, POLINA GIANNELOU, SOKRATIS GRIGORIADIS, AGNI PANTOU, GEORGE ANIFANDIS, PANAGIOTIS CHRISTOPOULOS, KONSTANTINOS PANTOS and MICHAEL KOUTSILIERIS
In Vivo November 2019, 33 (6) 1737-1749; DOI: https://doi.org/10.21873/invivo.11664
MARA SIMOPOULOU
1Department of Physiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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  • For correspondence: marasimopoulou{at}hotmail.com
KONSTANTINOS SFAKIANOUDIS
2Centre for Human Reproduction, Genesis Athens Clinic, Athens, Greece
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EVANGELOS MAZIOTIS
1Department of Physiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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PETROULA TSIOULOU
1Department of Physiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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POLINA GIANNELOU
1Department of Physiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece
2Centre for Human Reproduction, Genesis Athens Clinic, Athens, Greece
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SOKRATIS GRIGORIADIS
1Department of Physiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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AGNI PANTOU
2Centre for Human Reproduction, Genesis Athens Clinic, Athens, Greece
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GEORGE ANIFANDIS
3Department of Histology and Embryology, Faculty of Medicine, University of Thessaly, Larissa, Greece
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PANAGIOTIS CHRISTOPOULOS
1Department of Physiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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KONSTANTINOS PANTOS
2Centre for Human Reproduction, Genesis Athens Clinic, Athens, Greece
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MICHAEL KOUTSILIERIS
1Department of Physiology, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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    Figure 1.

    PRISMA flowchart regarding study selection.

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    Figure 2.

    Assessment of bias for each study included. Green coding with positive sign represents low risk of bias, yellow coding with question mark represents unclear risk of bias, and red coding with negative sign represents high risk of bias.

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    Figure 3.

    Review authors' judgements about each risk of biased item presented as percentages across all included studies.

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    Figure 4.

    Risk ratio and Forest plot regarding live birth rates. df: degrees of freedom; Z: z-statistic.

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    Figure 5.

    Risk ratio and forest plot regarding cumulative live birth and ongoing pregnancy rates.

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    Figure 6.

    Risk ratio and Forest plot regarding clinical pregnancy rates.

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    Figure 7.

    Risk ratio and forest plot regarding biochemical pregnancy rates.

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    Figure 8.

    Risk ratio and forest plot regarding miscarriages rates.

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Vol. 33, Issue 6
November-December 2019
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Investigating the Optimal Time for Intrauterine Human Chorionic Gonadotropin Infusion in Order to Improve IVF Outcome: A Systematic Review and Meta-Analysis
MARA SIMOPOULOU, KONSTANTINOS SFAKIANOUDIS, EVANGELOS MAZIOTIS, PETROULA TSIOULOU, POLINA GIANNELOU, SOKRATIS GRIGORIADIS, AGNI PANTOU, GEORGE ANIFANDIS, PANAGIOTIS CHRISTOPOULOS, KONSTANTINOS PANTOS, MICHAEL KOUTSILIERIS
In Vivo Nov 2019, 33 (6) 1737-1749; DOI: 10.21873/invivo.11664

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Investigating the Optimal Time for Intrauterine Human Chorionic Gonadotropin Infusion in Order to Improve IVF Outcome: A Systematic Review and Meta-Analysis
MARA SIMOPOULOU, KONSTANTINOS SFAKIANOUDIS, EVANGELOS MAZIOTIS, PETROULA TSIOULOU, POLINA GIANNELOU, SOKRATIS GRIGORIADIS, AGNI PANTOU, GEORGE ANIFANDIS, PANAGIOTIS CHRISTOPOULOS, KONSTANTINOS PANTOS, MICHAEL KOUTSILIERIS
In Vivo Nov 2019, 33 (6) 1737-1749; DOI: 10.21873/invivo.11664
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Keywords

  • Human chorionic gonadotropin
  • in vitro fertilization
  • live birth
  • meta-analysis
  • review
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