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Research ArticleExperimental Studies

A New Betulin Derivative Stimulates the Synthesis of Collagen in Human Fibroblasts Stronger than its Precursor

MAŁGORZATA DRĄG-ZALESIŃSKA, NINA REMBIAŁKOWSKA, SYLWIA BORSKA, JOLANTA SACZKO, MARCIN DRĄG, MARCIN PORĘBA and JULITA KULBACKA
In Vivo July 2019, 33 (4) 1087-1093; DOI: https://doi.org/10.21873/invivo.11577
MAŁGORZATA DRĄG-ZALESIŃSKA
1Faculty of Medicine, Department of Human Morphology and Embryology, Division of Histology and Embryology, Wroclaw Medical University, Wroclaw, Poland
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  • For correspondence: malgorzata.drag-zalesinka@umed.wroc.pl
NINA REMBIAŁKOWSKA
2Faculty of Pharmacy, Department of Molecular and Cellular Biology, Wroclaw Medical University, Wroclaw, Poland
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SYLWIA BORSKA
1Faculty of Medicine, Department of Human Morphology and Embryology, Division of Histology and Embryology, Wroclaw Medical University, Wroclaw, Poland
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JOLANTA SACZKO
2Faculty of Pharmacy, Department of Molecular and Cellular Biology, Wroclaw Medical University, Wroclaw, Poland
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MARCIN DRĄG
3Faculty of Chemistry, Department of Bioorganic Chemistry, Wroclaw University of Science and Technology, Wroclaw, Poland
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MARCIN PORĘBA
3Faculty of Chemistry, Department of Bioorganic Chemistry, Wroclaw University of Science and Technology, Wroclaw, Poland
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JULITA KULBACKA
2Faculty of Pharmacy, Department of Molecular and Cellular Biology, Wroclaw Medical University, Wroclaw, Poland
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Article Information

vol. 33 no. 4 1087-1093
DOI 
https://doi.org/10.21873/invivo.11577
PubMed 
31280196

Published By 
International Institute of Anticancer Research
Print ISSN 
0258-851X
Online ISSN 
1791-7549
History 
  • Received March 15, 2019
  • Revision received April 17, 2019
  • Accepted April 23, 2019
  • Published online July 6, 2019.

Copyright & Usage 
Copyright© 2019, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved

Author Information

  1. MAŁGORZATA DRĄG-ZALESIŃSKA1⇑,
  2. NINA REMBIAŁKOWSKA2,
  3. SYLWIA BORSKA1,
  4. JOLANTA SACZKO2,
  5. MARCIN DRĄG3,
  6. MARCIN PORĘBA3 and
  7. JULITA KULBACKA2
  1. 1Faculty of Medicine, Department of Human Morphology and Embryology, Division of Histology and Embryology, Wroclaw Medical University, Wroclaw, Poland
  2. 2Faculty of Pharmacy, Department of Molecular and Cellular Biology, Wroclaw Medical University, Wroclaw, Poland
  3. 3Faculty of Chemistry, Department of Bioorganic Chemistry, Wroclaw University of Science and Technology, Wroclaw, Poland
  1. Correspondence to: Malgorzata Drag-Zalesinska, MD, Ph.D. Division of Histology and Embryology, Department of Human Morphology and Embryology, Wroclaw Medical University, Chalubinskiego 6a, 50-368 Wroclaw, Poland. Tel: +48 717841683, Fax: +48 717840082, e-mail: malgorzata.drag-zalesinka{at}umed.wroc.pl
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A New Betulin Derivative Stimulates the Synthesis of Collagen in Human Fibroblasts Stronger than its Precursor
MAŁGORZATA DRĄG-ZALESIŃSKA, NINA REMBIAŁKOWSKA, SYLWIA BORSKA, JOLANTA SACZKO, MARCIN DRĄG, MARCIN PORĘBA, JULITA KULBACKA
In Vivo Jul 2019, 33 (4) 1087-1093; DOI: 10.21873/invivo.11577

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A New Betulin Derivative Stimulates the Synthesis of Collagen in Human Fibroblasts Stronger than its Precursor
MAŁGORZATA DRĄG-ZALESIŃSKA, NINA REMBIAŁKOWSKA, SYLWIA BORSKA, JOLANTA SACZKO, MARCIN DRĄG, MARCIN PORĘBA, JULITA KULBACKA
In Vivo Jul 2019, 33 (4) 1087-1093; DOI: 10.21873/invivo.11577
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Keywords

  • Betulin
  • betulinic acid
  • betulin derivative Betulin-Dab-NH2 (betulin ester with L-2,4-diaminobutyl acid)
  • collagen synthesis
  • human fibroblasts
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