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Research ArticleClinical Studies

Peak of Standardized Uptake Value in Oral Cancer Predicts Survival Adjusting for Pathological Stage

HIDENORI SUZUKI, TSUNEO TAMAKI, MASAMI NISHIO, SHINTARO BEPPU, NOBUAKI MUKOYAMA, NOBUHIRO HANAI, DAISUKE NISHIKAWA, YUSUKE KOIDE and YASUHISA HASEGAWA
In Vivo September 2018, 32 (5) 1193-1198; DOI: https://doi.org/10.21873/invivo.11363
HIDENORI SUZUKI
1Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
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  • For correspondence: hi.suzuki{at}aichi-cc.jp
TSUNEO TAMAKI
2Department of East Nagoya Imaging Diagnosis Center, Nagoya, Japan
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MASAMI NISHIO
3Department of Radiology, Nagoya Positron Emission Tomography Imaging Center, Nagoya, Japan
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SHINTARO BEPPU
1Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
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NOBUAKI MUKOYAMA
4Deparment of Othorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan
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NOBUHIRO HANAI
1Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
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DAISUKE NISHIKAWA
1Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
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YUSUKE KOIDE
1Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
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YASUHISA HASEGAWA
1Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan
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    Figure 1.

    Probability values of OS analysis using different cut-off levels for p-SUVmax, p-SUVpeak, p-MTV, p-TLG values. OS: Overall survival; p-SUVmax: maximum standardized uptake value of primary tumor; p-SUVpeak: peak standardized uptake value of primary tumor; p-MTV: metabolic tumor volume of primary tumor; p-TLG: total lesion glycolysis of primary tumor.

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    Figure 2.

    Pathological stage of IVB based on the UICC8th was associated with significantly shorter OS (p=0.01), and p-SUVpeak of ≥14.1 was associated with significantly lower OS (p<0.01), LRFS (p=0.02), DFS (p<0.01). UICC8th: The 8th edition of the Union for International Cancer Control, p-SUVpeak: peak standardized uptake value of primary tumor; OS: overall survival; LRFS: local recurrence-free survival; DFS: disease-free survival.

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Vol. 32, Issue 5
September-October 2018
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Peak of Standardized Uptake Value in Oral Cancer Predicts Survival Adjusting for Pathological Stage
HIDENORI SUZUKI, TSUNEO TAMAKI, MASAMI NISHIO, SHINTARO BEPPU, NOBUAKI MUKOYAMA, NOBUHIRO HANAI, DAISUKE NISHIKAWA, YUSUKE KOIDE, YASUHISA HASEGAWA
In Vivo Sep 2018, 32 (5) 1193-1198; DOI: 10.21873/invivo.11363

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Peak of Standardized Uptake Value in Oral Cancer Predicts Survival Adjusting for Pathological Stage
HIDENORI SUZUKI, TSUNEO TAMAKI, MASAMI NISHIO, SHINTARO BEPPU, NOBUAKI MUKOYAMA, NOBUHIRO HANAI, DAISUKE NISHIKAWA, YUSUKE KOIDE, YASUHISA HASEGAWA
In Vivo Sep 2018, 32 (5) 1193-1198; DOI: 10.21873/invivo.11363
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Keywords

  • Oral squamous cell carcinoma
  • 18F-FDG-PET/CT
  • SUVpeak
  • overall survival
  • UICC8th
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