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Research ArticleClinical Studies

Primary Gastric EBV-positive Diffuse Large B Cell Lymphoma (DLBCL) of the Elderly with Plasmablastic Differentiation

MING HU, JOSE TREVINO, LIJUN YANG, DENGFENG CAO, XIULI LIU and JINPING LAI
In Vivo March 2018, 32 (2) 413-417;
MING HU
1Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL, U.S.A.
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JOSE TREVINO
2Department of Surgery, University of Florida College of Medicine, Gainesville, FL, U.S.A.
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  • For correspondence: jinpinglai{at}ufl.edu jose.trevino{at}surgery.ufl.edu
LIJUN YANG
1Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL, U.S.A.
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DENGFENG CAO
3Department of Pathology, Immunology, and Laboratory Medicine, Washington University in Saint Louis, St. Louis, MO, U.S.A.
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XIULI LIU
1Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL, U.S.A.
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JINPING LAI
1Department of Pathology, Immunology, and Laboratory Medicine, University of Florida College of Medicine, Gainesville, FL, U.S.A.
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  • For correspondence: jinpinglai{at}ufl.edu jose.trevino{at}surgery.ufl.edu
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    Figure 1.

    Upper GI endoscopic appearance showing a 2-cm ulcerated lesion (left); Histologically, the ulcerated tissue showing center atypical lymphoid cells infiltrate (mid, HE stain, 100×) and the neoplastic cells are medium to large in size showing features of immunoblasts (right, HE stain, 400×).

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    Figure 2.

    Immunohistochemistry and in situ hybridization of the gastric ulcerated lymphoid tumor. The tumor cells are positive for CD20, EBER, CD30, CD138, MUM1 and Lambda, focally positive for Bcl-6. They are negative for Kappa (all, magnification 400×).

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In Vivo
Vol. 32, Issue 2
March-April 2018
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Primary Gastric EBV-positive Diffuse Large B Cell Lymphoma (DLBCL) of the Elderly with Plasmablastic Differentiation
MING HU, JOSE TREVINO, LIJUN YANG, DENGFENG CAO, XIULI LIU, JINPING LAI
In Vivo Mar 2018, 32 (2) 413-417;

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Primary Gastric EBV-positive Diffuse Large B Cell Lymphoma (DLBCL) of the Elderly with Plasmablastic Differentiation
MING HU, JOSE TREVINO, LIJUN YANG, DENGFENG CAO, XIULI LIU, JINPING LAI
In Vivo Mar 2018, 32 (2) 413-417;
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Keywords

  • stomach
  • diffuse large B cell lymphoma
  • plasmablastic lymphoma
  • ommunohistochemistry
  • in situ hybridization
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