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Research ArticleExperimental Studies

Variations in the Expression and Distribution Pattern of AQP5 in Acinar Cells of Patients with Sialadenosis

AFSHIN TEYMOORTASH, SUSANNE WIEGAND, MARTIN BORKELOH, MICHAEL BETTE, ANNETTE RAMASWAMY, SILKE STEINBACH-HUNDT, ANDREAS NEFF, JOCHEN A. WERNER and ROBERT MANDIC
In Vivo November 2012, 26 (6) 951-955;
AFSHIN TEYMOORTASH
1Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Giessen and Marburg, Marburg, Germany
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SUSANNE WIEGAND
1Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Giessen and Marburg, Marburg, Germany
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MARTIN BORKELOH
1Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Giessen and Marburg, Marburg, Germany
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MICHAEL BETTE
2Department of Molecular Neuroscience, Institute of Anatomy and Cell Biology, Philipps University, Marburg, Germany
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ANNETTE RAMASWAMY
3Institute of Pathology, University Hospital Giessen and Marburg, Marburg, Germany
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SILKE STEINBACH-HUNDT
1Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Giessen and Marburg, Marburg, Germany
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ANDREAS NEFF
4Department of Oral and Maxillofacial Surgery, University Hospital Giessen and Marburg, Marburg, Germany
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JOCHEN A. WERNER
1Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Giessen and Marburg, Marburg, Germany
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ROBERT MANDIC
1Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Giessen and Marburg, Marburg, Germany
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  • For correspondence: mandic@med.uni-marburg.de
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    Figure 1.

    Measurement of acinar diameter and surface area. Mean acinar diameter (A) and surface area (B) are increased in patients with sialadenosis. Differences did not reach significance.

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    Figure 2.

    Changes in the expression and distribution pattern of aquaporin 5 (AQP5) in sialadenosis tissues. Differences in the AQP5 distribution pattern were frequently observed in parotid tissues from patients with sialadenosis (#1-5 and 7-9) (see also Table I) compared with normal control tissues. No apical staining of AQP5 can be seen in the negative control of normal and sialadenosis tissues. Arrows indicate the apical region of acinar cells. Depicted in the first image are bars for size comparison.

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In Vivo: 26 (6)
In Vivo
Vol. 26, Issue 6
November-December 2012
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Variations in the Expression and Distribution Pattern of AQP5 in Acinar Cells of Patients with Sialadenosis
AFSHIN TEYMOORTASH, SUSANNE WIEGAND, MARTIN BORKELOH, MICHAEL BETTE, ANNETTE RAMASWAMY, SILKE STEINBACH-HUNDT, ANDREAS NEFF, JOCHEN A. WERNER, ROBERT MANDIC
In Vivo Nov 2012, 26 (6) 951-955;

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Variations in the Expression and Distribution Pattern of AQP5 in Acinar Cells of Patients with Sialadenosis
AFSHIN TEYMOORTASH, SUSANNE WIEGAND, MARTIN BORKELOH, MICHAEL BETTE, ANNETTE RAMASWAMY, SILKE STEINBACH-HUNDT, ANDREAS NEFF, JOCHEN A. WERNER, ROBERT MANDIC
In Vivo Nov 2012, 26 (6) 951-955;
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Keywords

  • Aquaporin 5
  • sialadenosis
  • Salivary gland
  • acinar gland
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