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Research ArticleClinical Studies

Extensive Sublingual Epidermoid Cyst – Diagnosis by Immunohistological Analysis and Proof by Podoplanin

ALEXANDRE T. ASSAF, MAX HEILAND, MARCO BLESSMANN, REINHARD E. FRIEDRICH, JOZEF ZUSTIN and AHMED AL-DAM
In Vivo March 2012, 26 (2) 323-326;
ALEXANDRE T. ASSAF
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  • For correspondence: a.assaf{at}uke.uni-hamburg.de
MAX HEILAND
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MARCO BLESSMANN
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REINHARD E. FRIEDRICH
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JOZEF ZUSTIN
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AHMED AL-DAM
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    Figure 1.

    Magnetic resonance imaging (sagittal and coronal view) of the patient after presentation, showing the midface and head and neck region, highlighting the giant epidermoid cyst located in the right sublingual region.

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    Figure 2.

    Intraoperative view of the intraoral cavity showing the superior part of the epidermoid cyst after incision of the right sublingual region before rupture of the cyst body.

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    Figure 3.

    Extension of the ruptured cyst body after total resection.

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    Figure 4.

    Epidermoid cyst (histopathology). A: The cyst contained flattened keratin lamellae and the wall was lined with keratinizing stratified squamous epithelial surface without atypia (haematoxylin-eosin, original magnification: ×200). B: Although several lymph vessels were highlighted with D2-40 (arrow), the cyst wall showed no podoplanin positive cells in non-inflamed areas. C: Adjacent to the ruptured cyst wall with secondary inflammatory changes (asterix), the basal epithelial layer showed strong reaction for podoplanin (arrows) (monoclonal podoplanin antibody D2-40, original magnification: ×200).

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In Vivo
Vol. 26, Issue 2
March-April 2012
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Extensive Sublingual Epidermoid Cyst – Diagnosis by Immunohistological Analysis and Proof by Podoplanin
ALEXANDRE T. ASSAF, MAX HEILAND, MARCO BLESSMANN, REINHARD E. FRIEDRICH, JOZEF ZUSTIN, AHMED AL-DAM
In Vivo Mar 2012, 26 (2) 323-326;

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Extensive Sublingual Epidermoid Cyst – Diagnosis by Immunohistological Analysis and Proof by Podoplanin
ALEXANDRE T. ASSAF, MAX HEILAND, MARCO BLESSMANN, REINHARD E. FRIEDRICH, JOZEF ZUSTIN, AHMED AL-DAM
In Vivo Mar 2012, 26 (2) 323-326;
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