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Research ArticleExperimental Studies

Xenotropic Murine Leukemia Virus-related Virus-associated Chronic Fatigue Syndrome Reveals a Distinct Inflammatory Signature

VINCENT C. LOMBARDI, KATHRYN S. HAGEN, KENNETH W. HUNTER, JOHN W. DIAMOND, JULIE SMITH-GAGEN, WEI YANG and JUDY A. MIKOVITS
In Vivo May 2011, 25 (3) 307-314;
VINCENT C. LOMBARDI
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  • For correspondence: vclombardi{at}wpinstitute.org vclombardi{at}gmail.com
KATHRYN S. HAGEN
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KENNETH W. HUNTER
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JOHN W. DIAMOND
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JULIE SMITH-GAGEN
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WEI YANG
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JUDY A. MIKOVITS
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    Figure 1.

    Two-dimensional SOTA method cluster analysis with Pearson correlation distance of 20 controls (Cont#), 20 XMRV/CFS patients (CFS#) and 20 XMRV/CFS patients with clonal populations of γ-δ T-cells (TCRG#), all chosen at random. Red indicates cytokines/chemokines that are increasingly up-regulated whereas blue indicates cytokines/chemokines that are increasingly down-regulated. Branching represents relatedness between cytokines/chemokines or relatedness between subjects.

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    Figure 2.

    Random Forest prediction. Horizontal bars represent the relative importance that each cytokine or chemokine contributes to the predictive nature of the signature.

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In Vivo
Vol. 25, Issue 3
May-June 2011
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Xenotropic Murine Leukemia Virus-related Virus-associated Chronic Fatigue Syndrome Reveals a Distinct Inflammatory Signature
VINCENT C. LOMBARDI, KATHRYN S. HAGEN, KENNETH W. HUNTER, JOHN W. DIAMOND, JULIE SMITH-GAGEN, WEI YANG, JUDY A. MIKOVITS
In Vivo May 2011, 25 (3) 307-314;

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Xenotropic Murine Leukemia Virus-related Virus-associated Chronic Fatigue Syndrome Reveals a Distinct Inflammatory Signature
VINCENT C. LOMBARDI, KATHRYN S. HAGEN, KENNETH W. HUNTER, JOHN W. DIAMOND, JULIE SMITH-GAGEN, WEI YANG, JUDY A. MIKOVITS
In Vivo May 2011, 25 (3) 307-314;
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