Thrombogenicity of Sirolimus-eluting Stents and Bare Metal Stents: Evaluation in the Early Phase after Stent Implantation

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Figure 1.
Platelet count (A), sP-selectin (B), thrombin-antithrombin III complex (TAT) (C), factor XIIa (D), SC5b-9 (E) and PMN-elastase (F) at the beginning (t=0) and after 90 minutes of blood circulation in the loops without a stent (Ctr), a bare metal stent (BMS) and with a sirolimus-eluting stent (SES). Data are presented as means ± standard error of mean. *p<0.05 vs. t=0; ^§p<0.05 vs. Ctr.
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Figure 2.
SEM of a bare-metal stent before (A) and after (B) blood exposure, and of a sirolimus-eluting stent before (C) and after (D) blood exposure. Both stent types were covered with a polymer fibrin net and cellular deposition and multiple platelet aggregates after being exposed for 90 minutes to the circulating blood. (Bar=50 μm).