Figure 2.
Effect of MRN-100 administration on plasma iron status of young and aged rats. Young and aged animals were treated with MRN-100 or given tap water only (control) for 40 days. Whole blood was then collected by heart puncture after light anesthesia using heparinized syringes. Hemolysates were used to assess A: total plasma iron levels, B: total iron-binding capacity (TIBC), C: transferrin saturation (TS) and D: ferritin levels. Data are means of 6 rats/group±SEM and are shown as a percentage of the young control rat group. a, A Significantly different from young control at p<0.05 and p<0.01 respectively; b, B significantly different from young treated at p<0.05 and p<0.01 respectively; c, C significantly different from aged control at p<0.05 and p<0.01 respectively; d, D significantly different from aged treated at p<0.05 and p<0.01 respectively.