Figure 3.
A-D. Cytotoxic activity of 7-bromo-2-(4-hydroxyanilino)tropone [16] (left panel) and 4-isopropyl-2-(2-hydroxyanilino)tropone [20] (right panel) after 24 (⋄), 48 (▵), 72 (□) or 96 (○) hours incubation. A: Human normal oral cells, B: human normal skin fibroblasts, C: human normal lung fibroblasts, D: human oral squamous cell carcinoma cell lines. Viable cell number (absorbance at 540 nm) was determined by MTT method. Control values are indicated on the intersection of x- and y-axes. Each value represents the mean of two independent experiments, which were conducted in triplicate.