Skip to main content

Main menu

  • Home
  • Current Issue
  • Archive
  • Info for
    • Authors
    • Advertisers
    • Editorial Board
  • Other Publications
    • Anticancer Research
    • Cancer Genomics & Proteomics
    • Cancer Diagnosis & Prognosis
  • More
    • IIAR
    • Conferences
  • About Us
    • General Policy
    • Contact
  • Other Publications
    • In Vivo
    • Anticancer Research
    • Cancer Genomics & Proteomics

User menu

  • Register
  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
In Vivo
  • Other Publications
    • In Vivo
    • Anticancer Research
    • Cancer Genomics & Proteomics
  • Register
  • Subscribe
  • My alerts
  • Log in
  • My Cart
In Vivo

Advanced Search

  • Home
  • Current Issue
  • Archive
  • Info for
    • Authors
    • Advertisers
    • Editorial Board
  • Other Publications
    • Anticancer Research
    • Cancer Genomics & Proteomics
    • Cancer Diagnosis & Prognosis
  • More
    • IIAR
    • Conferences
  • About Us
    • General Policy
    • Contact
  • Visit iiar on Facebook
  • Follow us on Linkedin
Research ArticleExperimental Studies

Potentiating Effect of Mentha arvensis and Chlorpromazine in the Resistance to Aminoglycosides of Methicillin - Resistant Staphylococcus aureus

HENRIQUE D.M. COUTINHO, JOSÉ G.M. COSTA, EDELTRUDES O. LIMA, VIVYANNE S. FALCÃO - SILVA and JOSÉ P. SIQUEIRA-JÚNIOR
In Vivo March 2009, 23 (2) 287-289;
HENRIQUE D.M. COUTINHO
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: hdmcoutinho@gmail.com
JOSÉ G.M. COSTA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
EDELTRUDES O. LIMA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
VIVYANNE S. FALCÃO - SILVA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
JOSÉ P. SIQUEIRA-JÚNIOR
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • PDF
Loading

Abstract

Background: This is the first report testing the antibiotic resistance-modifying activity of Mentha arvensis against MRSA (methicillin - resistant Staphylococcus aureus). Materials and Methods: In this study an ethanol extract of Mentha arvensis L. and chlorpromazine were tested for their antimicrobial activity alone or in combination with conventional antibiotics against MRSA strains. Results: A potentiating effect of this extract on gentamicin, kanamycin and neomycin was demonstrated. Similarly, a potentiating effect of chlorpromazine on the same aminoglycosides was observed, indicating the involvement of an efflux system in the resistance to these antibiotics. Conclusion: It is therefore suggested that extracts from M. arvensis could be used as a source of plant-derived natural products with resistance-modifying activity, such as in the case of aminoglycosides, constituting a new weapon against bacterial resistance to antibiotics, as with chlorpromazine.

  • Mentha arvensis
  • modifying antibiotic activity
  • ethanolic extract
  • aminoglycosides
  • chlorpromazine
  • Received September 9, 2008.
  • Revision received January 13, 2009.
  • Accepted February 13, 2009.
  • Copyright © 2009 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved
View Full Text
PreviousNext
Back to top

In this issue

In Vivo: 23 (2)
In Vivo
Vol. 23, Issue 2
March-April 2009
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Back Matter (PDF)
  • Front Matter (PDF)
Print
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on In Vivo.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Potentiating Effect of Mentha arvensis and Chlorpromazine in the Resistance to Aminoglycosides of Methicillin - Resistant Staphylococcus aureus
(Your Name) has sent you a message from In Vivo
(Your Name) thought you would like to see the In Vivo web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
8 + 8 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Citation Tools
Potentiating Effect of Mentha arvensis and Chlorpromazine in the Resistance to Aminoglycosides of Methicillin - Resistant Staphylococcus aureus
HENRIQUE D.M. COUTINHO, JOSÉ G.M. COSTA, EDELTRUDES O. LIMA, VIVYANNE S. FALCÃO - SILVA, JOSÉ P. SIQUEIRA-JÚNIOR
In Vivo Mar 2009, 23 (2) 287-289;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Reprints and Permissions
Share
Potentiating Effect of Mentha arvensis and Chlorpromazine in the Resistance to Aminoglycosides of Methicillin - Resistant Staphylococcus aureus
HENRIQUE D.M. COUTINHO, JOSÉ G.M. COSTA, EDELTRUDES O. LIMA, VIVYANNE S. FALCÃO - SILVA, JOSÉ P. SIQUEIRA-JÚNIOR
In Vivo Mar 2009, 23 (2) 287-289;
del.icio.us logo Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Materials and Methods
    • Results
    • Discussion
    • References
  • Figures & Data
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Google Scholar

More in this TOC Section

  • Non-invasively Imageable Tibia-tumor-fragment Implantation Experimental-bone-metastasis Mouse Model of GFP-expressing Prostate Cancer
  • Protective Effects of Gamma-mangostin on Hydrogen Peroxideinduced Cytotoxicity in Human Retinal Pigment Epithelial Cells
  • The First Mouse Model of Meckel’s Diverticulum Carcinoma
Show more Experimental Studies

Similar Articles

In Vivo

© 2022 In Vivo

Powered by HighWire