Skip to main content

Main menu

  • Home
  • Current Issue
  • Archive
  • Info for
    • Authors
    • Editorial Policies
    • Advertisers
    • Editorial Board
    • Special Issues
  • Journal Metrics
  • Other Publications
    • Anticancer Research
    • Cancer Genomics & Proteomics
    • Cancer Diagnosis & Prognosis
  • More
    • IIAR
    • Conferences
  • About Us
    • General Policy
    • Contact
  • Other Publications
    • In Vivo
    • Anticancer Research
    • Cancer Genomics & Proteomics

User menu

  • Register
  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
In Vivo
  • Other Publications
    • In Vivo
    • Anticancer Research
    • Cancer Genomics & Proteomics
  • Register
  • Subscribe
  • My alerts
  • Log in
  • My Cart
In Vivo

Advanced Search

  • Home
  • Current Issue
  • Archive
  • Info for
    • Authors
    • Editorial Policies
    • Advertisers
    • Editorial Board
    • Special Issues
  • Journal Metrics
  • Other Publications
    • Anticancer Research
    • Cancer Genomics & Proteomics
    • Cancer Diagnosis & Prognosis
  • More
    • IIAR
    • Conferences
  • About Us
    • General Policy
    • Contact
  • Visit iiar on Facebook
  • Follow us on Linkedin
Review Article

γ-H2AX - A Novel Biomarker for DNA Double-strand Breaks

LINDA J. KUO and LI-XI YANG
In Vivo May 2008, 22 (3) 305-309;
LINDA J. KUO
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
LI-XI YANG
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: yangl{at}cpmcri.org
  • Article
  • Info & Metrics
  • PDF
Loading

Article Information

vol. 22 no. 3 305-309
PMID 
18610740

Published By 
International Institute of Anticancer Research
Print ISSN 
0258-851X
Online ISSN 
1791-7549
History 
  • Received December 27, 2007
  • Revision received March 18, 2008
  • Accepted March 21, 2008
  • Published online May 1, 2008.

Copyright & License 
Copyright © 2008 The Author(s). Published by the International Institute of Anticancer Research.

Author Information

  1. LINDA J. KUO1 and
  2. LI-XI YANG1,2
  1. 1Radiobiology Laboratory, California Pacific Medical Center Research Institute, San Francisco, CA 94118
  2. 2St. Mary's Medical Center, San Francisco, CA 94117, U.S.A.
  1. Correspondence to: Dr. Lixi Yang, Radiobiology Laboratory, California Pacific Medical Center Research Institute, 3801 Sacramento Street, San Francisco, CA 94118, U.S.A. Tel: +415 600 6203, Fax: +415 600 6215, e-mail: yangl{at}cpmcri.org

Statistics from Altmetric.com

Cited By...

  • 1167 Citations
  • Citations
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

PreviousNext
Back to top

In this issue

In Vivo
Vol. 22, Issue 3
May-June 2008
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on In Vivo.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
γ-H2AX - A Novel Biomarker for DNA Double-strand Breaks
(Your Name) has sent you a message from In Vivo
(Your Name) thought you would like to see the In Vivo web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
7 + 9 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Citation Tools
γ-H2AX - A Novel Biomarker for DNA Double-strand Breaks
LINDA J. KUO, LI-XI YANG
In Vivo May 2008, 22 (3) 305-309;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Reprints and Permissions
Share
γ-H2AX - A Novel Biomarker for DNA Double-strand Breaks
LINDA J. KUO, LI-XI YANG
In Vivo May 2008, 22 (3) 305-309;
Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
  • Info & Metrics
  • PDF

Related Articles

Cited By...

  • PARP1-mediated 5 flap dynamics facilitate Okazaki fragment maturation
  • Novel polymeric fluoropyrimidine CF10 demonstrates superior therapeutic index and survival advantage in patient-derived models of 5-fluorouracil-refractory colorectal cancer
  • Biomimetic model for the identification of distinctive microenvironmental factors in glioblastoma radiosensitivity
  • XPF mediates 3 flap processing for FEN1-independent Okazaki fragment maturation
  • Senataxin is required for optimal class switch recombination to the immunoglobulin A isotype
  • A Lung Tumor-on-a-Chip Model Recapitulates the Effect of Hypoxia on Radiotherapy Response and FDG-PET Imaging
  • PIWIL2 downregulation in colon cancer promotes transposon activity and pro-tumorigenic phenotypes
  • Recapitulation of Cellular Senescence, Inflammation, and Fibrosis in Human Kidney-Derived Tubuloids by Repeated Cisplatin Treatment: A Novel Pathophysiological Model for Sensing Nephrotoxicity and Drug Screening
  • CD8+ T cells drive myofibroblast activation and contraction via JAK/STAT3 and TGF{beta} signaling
  • G-quadruplexes represent promising new targets to overcome multidrug-resistant fungal infections
  • Length of ischemic time is critical for accurate determination of homologous recombination capacity by immunostaining in FFPE tumor samples
  • Mitochondrial DNA is a sensitive surrogate and oxidative stress target in oral cancer cells
  • Pre and Post-high-intensity Interval Training Delays Colon Tumor Onset in a Syngeneic Mouse Model
  • Diverging the anthracycline class of anti-cancer drugs for superior survival of acute myeloid leukemia patients
  • Endothelial-secreted Endocan protein acts as a PDGFR alpha ligand and regulates vascularity, radioresistance, and regional phenotype in glioblastoma
  • PKC{delta} regulates chromatin remodeling and DNA repair through SIRT6
  • Levamisole suppresses activation and proliferation of human T cells by the induction of a p53-dependent DNA damage response
  • The RNA helicase DDX1 associates with the nuclear RNA exosome and modulates R-loops
  • Stretch-injury promotes activation of microglia with enhanced phagocytic and synaptic stripping activities
  • Atherosclerosis is a smooth muscle cell-driven tumor-like disease
  • Metabolic clogging of mannose triggers genomic instability via dNTP loss in human cancer cells
  • STAT3-mediated upregulation of the AIM2 DNA sensor links innate immunity with cell migration to promote epithelial tumourigenesis
  • Spinal cord extracts of amyotrophic lateral sclerosis spread TDP-43 pathology in cerebral organoids
  • Induction of a CD8 T cell intrinsic DNA damage and repair response is associated with clinical response to PD-1 blockade in uterine cancer
  • Early loss of endogenous NAD+ following rotenone treatment leads to Sarm1 activation that is ameliorated by PARP inhibition
  • Targeting Chemotherapy to Decondensed H3K27me3-Marked Chromatin of AML Cells Enhances Leukemia Suppression
  • Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell death
  • MicroRNAs Involved in Small-cell Lung Cancer as Possible Agents for Treatment and Identification of New Targets
  • Heterogeneous nuclear ribonucleoprotein E1 binds polycytosine DNA and monitors genome integrity
  • Nuclear lamin isoforms differentially contribute to LINC complex-dependent nucleocytoskeletal coupling and whole cell mechanics
  • Time- and cell-dependent atypia and cell death are caused by progressive deficiency in DNA replication
  • Kinetics of osmotic stress regulate a cell fate switch of cell survival
  • Mapping sites of carboxymethyllysine modification on proteins reveals its consequences for proteostasis and cell proliferation
  • Preclinical Antitumor Activity and Biodistribution of a Novel Anti-GCC Antibody-Drug Conjugate in Patient-derived Xenografts
  • HIV Vpr Modulates the Host DNA Damage Response at Two Independent Steps to Damage DNA and Repress Double-Strand DNA Break Repair
  • ASH2L drives proliferation and sensitivity to bleomycin and other genotoxins in Hodgkins lymphoma and testicular cancer cells
  • Kinetics of osmotic stress regulates a cell fate switch of cell survival
  • Dissociation of the AhR/ARNT complex by TGF-{beta}/Smad signaling represses CYP1A1 gene expression and inhibits benze[a]pyrene-mediated cytotoxicity
  • Uncoupling DNA damage from chromatin damage to detoxify doxorubicin
  • The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation
  • HIV Vpr modulates the host DNA damage response at two independent steps to damage DNA and repress double-strand DNA break repair
  • Methylglyoxal induces nuclear accumulation of p53 and {gamma}H2AX in normal and cancer cells
  • Targeting the MET Receptor Tyrosine Kinase as a Strategy for Radiosensitization in Locoregionally Advanced Head and Neck Squamous Cell Carcinoma
  • Olaparib Potentiates Anticancer Drug Cytotoxicity via 53BP1 in Oesophageal Squamous Cell Carcinoma Cells
  • WD40 protein Wuho controls germline homeostasis via TRIM-NHL tumor suppressor Mei-p26 in Drosophila
  • Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair
  • Identification of the hyaluronic acid pathway as a therapeutic target for facioscapulohumeral muscular dystrophy
  • Analysis of DNA Damage Responses After Boric Acid-mediated Boron Neutron Capture Therapy in Hepatocellular Carcinoma
  • DNA methyltransferase inhibitors induce a BRCAness phenotype that sensitizes NSCLC to PARP inhibitor and ionizing radiation
  • Chemically induced neurite-like outgrowth reveals a multicellular network function in patient-derived glioblastoma cells
  • Radiation-Induced DNA Damage and Repair Effects on 3D Genome Organization
  • Cyclin A2/Cdk1 is Essential for the in vivo S Phase Entry by Phosphorylating Top2a
  • Chemically-induced Neurite-like Outgrowth Reveals Multicellular Network Function in Patient-derived Glioblastoma Cells
  • The mouse HP1 proteins are not required for cell viability but are essential for preventing liver tumorigenesis
  • The DNA repair associated protein Gadd45{gamma} regulates the temporal coding of immediate early gene expression and is required for the consolidation of associative fear memory
  • The DNA Repair-Associated Protein Gadd45{gamma} Regulates the Temporal Coding of Immediate Early Gene Expression within the Prelimbic Prefrontal Cortex and Is Required for the Consolidation of Associative Fear Memory
  • Enhanced Radiosensitivity in Solid Tumors using a Tumor-selective Alkyl Phospholipid Ether Analog
  • Selective depletion of metastatic stem cells as therapy for human colorectal cancer
  • Application of a radiosensitivity flow assay in a patient with DNA ligase 4 deficiency
  • Exploring the Role of Enzalutamide in Combination with Radiation Therapy: An In Vitro Study
  • Superresolution imaging of individual replication forks reveals unexpected prodrug resistance mechanism
  • Novel YAP1 Activator, Identified by Transcription-Based Functional Screen, Limits Multiple Myeloma Growth
  • The Role of DNA Polymerase {beta} in Neural Genome Stability
  • Jadomycins Inhibit Type II Topoisomerases and Promote DNA Damage and Apoptosis in Multidrug-Resistant Triple-Negative Breast Cancer Cells
  • 89Zr-anti-{gamma}H2AX-TAT but not 18F-FDG Allows Early Monitoring of Response to Chemotherapy in a Mouse Model of Pancreatic Ductal Adenocarcinoma
  • Mitochondrial Superoxide Increases Age-Associated Susceptibility of Human Dermal Fibroblasts to Radiation and Chemotherapy
  • Nuclear {alpha}-catenin mediates the DNA damage response via {beta}-catenin and nuclear actin
  • FOXO3 Transcription Factor Is Essential for Protecting Hematopoietic Stem and Progenitor Cells from Oxidative DNA Damage
  • Posttranscriptional Upregulation of p53 by Reactive Oxygen Species in Chronic Lymphocytic Leukemia
  • RK-33 Radiosensitizes Prostate Cancer Cells by Blocking the RNA Helicase DDX3
  • The plant-specific CDKB1-CYCB1 complex mediates homologous recombination repair in Arabidopsis
  • The RNA-Binding Proteins Zfp36l1 and Zfp36l2 Enforce the Thymic {beta}-Selection Checkpoint by Limiting DNA Damage Response Signaling and Cell Cycle Progression
  • A wide reprogramming of histone H3 modifications during male meiosis I in rice is dependent on the Argonaute protein MEL1
  • Amplification of TLK2 Induces Genomic Instability via Impairing the G2-M Checkpoint
  • DNA repair of myeloma plasma cells correlates with clinical outcome: the effect of the nonhomologous end-joining inhibitor SCR7
  • SGEF Is Regulated via TWEAK/Fn14/NF-{kappa}B Signaling and Promotes Survival by Modulation of the DNA Repair Response to Temozolomide
  • Activation of the Constitutive Androstane Receptor Increases the Therapeutic Index of CHOP in Lymphoma Treatment
  • Functional Roles of the E3 Ubiquitin Ligase UBR5 in Cancer
  • Small-Molecule NSC59984 Restores p53 Pathway Signaling and Antitumor Effects against Colorectal Cancer via p73 Activation and Degradation of Mutant p53
  • Macrophages Regulate the Systemic Response to DNA Damage by a Cell Nonautonomous Mechanism
  • Nedd4 Family Interacting Protein 1 (Ndfip1) Is Required for Ubiquitination and Nuclear Trafficking of BRCA1-associated ATM Activator 1 (BRAT1) during the DNA Damage Response
  • WWOX, the common fragile site FRA16D gene product, regulates ATM activation and the DNA damage response
  • A Phase I/II Trial of Belinostat in Combination with Cisplatin, Doxorubicin, and Cyclophosphamide in Thymic Epithelial Tumors: A Clinical and Translational Study
  • Topoisomerase IIbeta is required for proper retinal development and survival of postmitotic cells
  • Modified Arabinoxylan from Rice Bran, MGN-3/Biobran, Sensitizes Metastatic Breast Cancer Cells to Paclitaxel In Vitro
  • Google Scholar
In Vivo

© 2026 In Vivo

Powered by HighWire