Skip to main content

Main menu

  • Home
  • Current Issue
  • Archive
  • Info for
    • Authors
    • Editorial Policies
    • Advertisers
    • Editorial Board
  • Other Publications
    • Anticancer Research
    • Cancer Genomics & Proteomics
    • Cancer Diagnosis & Prognosis
  • More
    • IIAR
    • Conferences
  • About Us
    • General Policy
    • Contact
  • Other Publications
    • In Vivo
    • Anticancer Research
    • Cancer Genomics & Proteomics

User menu

  • Register
  • Subscribe
  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
In Vivo
  • Other Publications
    • In Vivo
    • Anticancer Research
    • Cancer Genomics & Proteomics
  • Register
  • Subscribe
  • My alerts
  • Log in
  • My Cart
In Vivo

Advanced Search

  • Home
  • Current Issue
  • Archive
  • Info for
    • Authors
    • Editorial Policies
    • Advertisers
    • Editorial Board
  • Other Publications
    • Anticancer Research
    • Cancer Genomics & Proteomics
    • Cancer Diagnosis & Prognosis
  • More
    • IIAR
    • Conferences
  • About Us
    • General Policy
    • Contact
  • Visit iiar on Facebook
  • Follow us on Linkedin
Research Article

A Phase II Clinical Study on Relapsed Malignant Gliomas Treated with Electro-hyperthermia

GIAMMARIA FIORENTINI, PETROS GIOVANIS, SUSANNA ROSSI, PATRIZIA DENTICO, RAFFAELE PAOLA, GINA TURRISI and PAOLO BERNARDESCHI
In Vivo November 2006, 20 (6A) 721-724;
GIAMMARIA FIORENTINI
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: oncologiaempoli@usl11.toscana.it
PETROS GIOVANIS
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
SUSANNA ROSSI
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
PATRIZIA DENTICO
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
RAFFAELE PAOLA
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
GINA TURRISI
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
PAOLO BERNARDESCHI
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info & Metrics
  • PDF
Loading

Abstract

The purpose of this study was to evaluate the activity and toxicity of electro-hyperthermia (ET) on relapsed malignant glioma patients. Twelve patients with histologically diagnosed malignant glioma entered the study. Eight patients had glioblastoma multiforme, two had anaplastic astrocytoma grade III and two had anaplastic oligodendroglioma. All patients were pre-treated with temozolamide-based chemotherapy and radiotherapy. Hyperthermia with short radiofrequency waves of 13.56 MHz was applied using a capacitive coupling technique keeping the skin surface at 20°C. The applied power ranged between 40-150 Watts and the calculated average equivalent temperature in the tumours was above 40°C for more than 90% of the treatment duration. One complete remission and 2 partial remission were achieved, with a response rate of 25%. The median duration of response was 10 months (range 4-32). The median survival of the entire patient population was 9 months, with 25% survival rate at 1 year. ET appears to have some effectiveness in adults with relapsed malignant glioma.

  • Hyperthermia
  • malignant glioma
  • electro-hyperthermia

Footnotes

  • Received July 10, 2006.
  • Revision received October 24, 2006.
  • Accepted October 25, 2006.
  • Copyright © 2006 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved
PreviousNext
Back to top

In this issue

In Vivo: 20 (6A)
In Vivo
Vol. 20, Issue 6A
November-December 2006
  • Table of Contents
  • Table of Contents (PDF)
  • Index by author
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for your interest in spreading the word on In Vivo.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
A Phase II Clinical Study on Relapsed Malignant Gliomas Treated with Electro-hyperthermia
(Your Name) has sent you a message from In Vivo
(Your Name) thought you would like to see the In Vivo web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
1 + 4 =
Solve this simple math problem and enter the result. E.g. for 1+3, enter 4.
Citation Tools
A Phase II Clinical Study on Relapsed Malignant Gliomas Treated with Electro-hyperthermia
GIAMMARIA FIORENTINI, PETROS GIOVANIS, SUSANNA ROSSI, PATRIZIA DENTICO, RAFFAELE PAOLA, GINA TURRISI, PAOLO BERNARDESCHI
In Vivo Nov 2006, 20 (6A) 721-724;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Reprints and Permissions
Share
A Phase II Clinical Study on Relapsed Malignant Gliomas Treated with Electro-hyperthermia
GIAMMARIA FIORENTINI, PETROS GIOVANIS, SUSANNA ROSSI, PATRIZIA DENTICO, RAFFAELE PAOLA, GINA TURRISI, PAOLO BERNARDESCHI
In Vivo Nov 2006, 20 (6A) 721-724;
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
  • Info & Metrics
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Clinical and economic evaluation of modulated electrohyperthermia concurrent to dose-dense temozolomide 21/28 days regimen in the treatment of recurrent glioblastoma: a retrospective analysis of a two-centre German cohort trial with systematic comparison and effect-to-treatment analysis
  • Fighting Fire with Fire: The Revival of Thermotherapy for Gliomas
  • Google Scholar

Similar Articles

In Vivo

© 2023 In Vivo

Powered by HighWire