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Research ArticleClinical Studies

Voriconazole Curative Treatment for Acremonium Species Keratitis Developed in a Patient with Concomitant Staphylococcus aureus Corneal Infection: A Case Report

ANNA CRETÌ, VINCENZO ESPOSITO, MARIA BOCCHETTI, GIANLUCA BALDI, PASQUALE DE ROSA, ROBERTO PARRELLA and ANTONIO CHIRIANNI
In Vivo January 2006, 20 (1) 169-171;
ANNA CRETÌ
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VINCENZO ESPOSITO
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  • For correspondence: esposvin{at}libero.it
MARIA BOCCHETTI
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GIANLUCA BALDI
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PASQUALE DE ROSA
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ROBERTO PARRELLA
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ANTONIO CHIRIANNI
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Abstract

The case of a 49-year-old male Caucasian, with more than a 3-year history of recurrent keratoconjunctivitis treated with steroids, antibiotics and midriatics, is reported. A combined Acremonium spp. and S. aureus infection was detected. After unsuccessful therapy with fluconazole, the Acremonium spp. infection was eradicated by voriconazole treatment. To our knowledge, this is the first case report of complete regression of this kind of infection by the use of voriconazole. Therefore, we strongly recommend, in the event of a compatible clinical picture, laboratory testing for mycetes even in the absence of traumatic events, and the use of the new generation azoles, in order avoid a keratoplasty intervention and disease progression to severe endophthalmitis.

  • Voriconazole
  • Acremonium
  • keratitis
  • Staphylococcus aureus
  • corneal infection

Footnotes

  • Received July 15, 2005.
  • Revision received October 6, 2005.
  • Accepted October 12, 2005.
  • Copyright © 2006 The Author(s). Published by the International Institute of Anticancer Research.
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January-February 2006
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Voriconazole Curative Treatment for Acremonium Species Keratitis Developed in a Patient with Concomitant Staphylococcus aureus Corneal Infection: A Case Report
ANNA CRETÌ, VINCENZO ESPOSITO, MARIA BOCCHETTI, GIANLUCA BALDI, PASQUALE DE ROSA, ROBERTO PARRELLA, ANTONIO CHIRIANNI
In Vivo Jan 2006, 20 (1) 169-171;

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Voriconazole Curative Treatment for Acremonium Species Keratitis Developed in a Patient with Concomitant Staphylococcus aureus Corneal Infection: A Case Report
ANNA CRETÌ, VINCENZO ESPOSITO, MARIA BOCCHETTI, GIANLUCA BALDI, PASQUALE DE ROSA, ROBERTO PARRELLA, ANTONIO CHIRIANNI
In Vivo Jan 2006, 20 (1) 169-171;
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